PHAGOCYTOSIS-INITIATED TUMOR HYBRID CELLS ACQUIRE A C-MYC-MEDIATED QUASI-POLARIZATION STATE FOR IMMUNOEVASION AND DISTANT DISSEMINATION

Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination

Abstract While macrophage phagocytosis is an immune defense mechanism against invading cellular organisms, cancer cells expressing the CD47 ligand send forward signals to repel this engulfment.Here we report that the reverse signaling using CD47 as a receptor additionally enhances a pro-survival function of prostate cancer cells under phagocytic at

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Dietary supplementation with inulin improves burn-induced skeletal muscle atrophy by regulating gut microbiota disorders

Abstract Inulin, as a prebiotic, could modulate the gut microbiota.Burn injury leads to gut microbiota disorders and skeletal muscle catabolism.Therefore, whether inulin can improve burn-induced muscle atrophy by regulating microbiota disorders remains unknown.This study aimed to clarify that inulin intake alleviates gut microbiota disorders and sk

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